To make it back home to Levi’s Stadium for Super Bowl 60, the San Francisco 49ers are once again faced with the tall task of another road playoff game. After the 49ers’ Wild Card win last Sunday in Philadelphia,

Fleming reports, citing a "bevy of medical experts," that the science doesn't support the connection. The bigger logical flaw seems to be that the 49ers have practiced in the same facility since 1988. They've won three Super Bowls, and qualified for three others, practicing there.

FILE: USC Trojan quarterback Sam Darnold talks with his high school coach, San Clemente's Jaime Ortiz, during USC Spring practice on Brian Kennedy/Howard Jones Field on the campus of the University of Southern California in Los Angeles on Saturday, April 1, 2017.

Two of Brock Purdy's worst performances in an otherwise stellar career came when he matched up against a Mike Macdonald-coached defense.

Zach Charbonnet, RB for the Seahawks, had a strong close to the regular season, and that should carry into this playoff matchup. In his last two outings, he had 110 and 74 rushing yards. His 74 rushing yards were from 17 carries, and in a win against no other team than the 49ers. He also had the lone TD scored in Seattle’s 13-3 win.

The Pittsburgh Steelers are searching for a new head coach following Mike Tomlin's departure, with 49ers defensive coordinator Klay Kubiak emerging as a candidate.

The San Francisco 49ers are among the most injury-prone teams in the NFL. The weirdest claim being made to explain it points at a Santa Clara power substation as the culprit.

Significant changes will need to be made by the San Francisco 49ers in their third matchup with the Seattle Seahawks. Their performance in Week 18 was arguably