As many as 1 in 4 cancers are driven by mutations in the SWI/SNF chromatin-remodeling complex, which controls access to DNA.

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the ...

Findings surrounding the epigenetic inheritance that takes place in plants may have implications for agriculture, food supplies, and the environment. Now, new research has uncovered a key mechanism in ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, determines which genetic instructions are activated. When this fails, the wrong ...

In a recent article published in Nature Genetics, researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of ...

Protein condensates (shown here in a microscope image) are critical to the process of gene expression in cells, and condensate formation depends on proteins’ intrinsically disordered regions, a new ...

Anyone who’s ever scraped their knee on a dirty playground is familiar with the stinging inflammation that manifests soon after the injury. It’s the immune system’s effort to restrict and neutralize ...

Our cells are usually frantically working to sustain life. Part of this work includes dividing, a process that creates more cells to support our growth when we are children or to replace old, worn-out ...