Refining the uncharted landscape of human transcription factors—strategic framework created for future prioritization

The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across ...
News Medical

The role of transcription factors in next-gen drug discovery

Transcription Factors (TFs) are pivotal regulators of gene expression and have been implicated in a variety of diseases, including cancer, neurological disorders, autoimmune conditions, and metabolic ...
eLife

The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity

Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States ...
Fred Hutch

Rewriting the story about the molecules that turn genes on and off

Some things just go together like “rock and roll” and “fish and chips” or, in molecular biology, “transcription factors” and the “nearby genes they regulate.” The standard, simplified story goes like ...
FierceBiotech

Roche teams up with transcription factor trailblazer Flare in new $1.8B-plus cancer pact

Roche and Flare Therapeutics are igniting a partnership worth more than $1.8 billion in biobucks with hopes of discovering new small molecule cancer treatments via previously undruggable transcription ...