Please provide your email address to receive an email when new articles are posted on . Both excessive and long-term alcohol consumption, as well as any spirit consumption, predict the development of ...

The characteristics of the sample are presented in Table 1 and Table 2. The average age was 60.9 years, and patients had been diagnosed an average of 12 years. Most were male (81%), and 38% were ...

Credit: Shutterstock. The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum ...

Please provide your email address to receive an email when new articles are posted on . One of the thrilling aspects of scientific discovery is that it can come from almost anywhere, and almost anyone ...

— REDUCE 1 is a study running in parallel with REDUCE 2 to evaluate pozdeutinurad's efficacy in lowering serum urate (sUA) levels and resolution of target tophi in gout patients — SAN DIEGO, July 1, ...

Bone erosion in patients with gout and tophi was associated with tophi duration, drinking history, ulceration, and serum creatinine levels. Bone erosion in patients with gout and tophi was associated ...

Krystexxa, a PEGylated uric acid specific enzyme, is approved for the treatment of refractory chronic gout. One study retrospectively analyzed data from two 6-month, randomized clinical trials that ...

The MarketWatch News Department was not involved in the creation of this content. -- Enrollment complete in the replicate REDUCE 1 and REDUCE 2 Phase 3 studies with pivotal data expected in Q2 2026 ...

Male doctor with senior male patient. Suneet Grewal, MD, provides a deeper insight into the impact of uncontrolled gout on the quality of life of patients and the importance of having an open dialogue ...

Background: The prevalence of gout is increasing, and most research on the associated burden has focused on serum urate (sUA) levels. The present study quantifies the impact of the presence of tophi ...