Inefficient mitochondrial apoptosis is a key determinant in therapeutic success of a number of anticancer regimens. Mitochondrial apoptosis is tightly controlled by the Bcl-2 protein family. Bcl-2 ...
Lenalidomide is a cornerstone therapy for multiple myeloma (MM) and other hematologic malignancies, but conventional oral dosing is limited by high peak plasma concentrations, rapid clearance, and ...
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