Human cytomegalovirus (HCMV) is a ubiquitous member of the Betaherpesvirinae that infects the majority of the human population. Although primary infection is often asymptomatic in immunocompetent ...

Human cytomegalovirus (HCMV) is an important human pathogen and a paradigm of intrinsic, innate, and adaptive viral immune evasion. Here, we employed multiplexed tandem mass tag-based proteomics to ...

Human cytomegalovirus (HCMV)—a name that sounds like it was derived straight from a 1970s low-budget sci-fi movie. And while this microbial pathogen does quite invoke the same fear as say Ebola, HCMV ...

Human cytomegalovirus has a complex double-stranded DNA genome of ≈240,000 bp that contains ≈150 ORFs likely to encode proteins, most of whose functions are not well understood. We have used an ...

Current drugs for treating human cytomegalovirus (HCMV) infections are limited by resistance and treatment-associated toxicities. In developing mechanistically novel HCMV antivirals, the authors of ...

Mathematical modeling can be a powerful tool for taking a systems-based approach to understanding virus-host interactions and simulating clinical trials that test therapeutic efficacy. Drs. Elizabeth ...

Credit: Getty Images This review provides a concise overview of the epidemiology, etiology, history, diagnostic criteria, and management of CMV infection in solid organ transplant recipients.

Considering the detrimental effects of cCMV on affected children and families, the lack of treatment options, and the related health-care costs, the primary-care provider should focus on preventing ...

− If Approved, Maribavir Would be the First and Only Inhibitor of CMV-specific UL97 Protein Kinase in the EU for Treatment of Adults with Post-transplant CMV Refractory (With or Without Resistance) to ...