A major, multicenter study of microarray performance is a first step in translating the technology from bench to bedside. No technology embodies the rise of 'omic' science more than the DNA microarray ...

The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...

Companies in the microarray sector are trying to take the technology out of core facilities and put it into the hands of individual researchers by developing technologies such as smaller, less-costly ...

Nature uses a common framework when building organisms as different as yeast, worms, fruit flies, mice, and humans. This makes it possible for scientists to learn about how our own genes work by ...

Different applications have different requirements, so researchers need to carefully weigh their options when deciding whether to switch to a new platform. [© WavebreakmediaMicro – Fotolia.com] With ...

With respect to assay development, quality assurance and, ultimately, clinical adoption, the primary subject of this review, these advantages are critical. Implicit with these advantages, TMAs enable ...

Copy number variation (CNV) assessment is a critical component of precision medicine in almost all cancer types. For instance, copy number gain is a well described drug resistance mechanism to ...

To address concerns about microarray reliability, several groups have attempted to evaluate and compare different platforms, but these efforts themselves are open to question. "Each one of those ...

"The use of genomic microarrays was shown to be useful in the included study population for providing prognostic information regarding time to first treatment. This technique could, with extensive ...