The model has Buffalo winning in 55% of its simulations, but the Steelers offer more value on the money line at +152. Pittsburgh covers the 3.5-point spread in 53% of the simulations, while there's an even 50% split between Over and Under outcomes.

While the Steelers aren't competing on Thanksgiving in 2025, fans can give thanks that Pittsburgh has been a part of some exciting matchups on the holiday in years past — although most haven't gone their way.