Yasmeen Rahimi, João-Paulo G. Camporez, Max C. Petersen, Dominik Pesta, Rachel J. Perry, Michael J. Jurczak, Gary W. Cline, Gerald I. Shulman Proceedings of the National Academy of Sciences of the ...
Pyruvate dictates redox balance and cell size, establishing metabolism as a dominant regulator of cellular fitness, unveiling new strategies to modulate cancer, regeneration, and diabetes.
The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application for SL1009 (sodium dichloroacetate oral solution) for the treatment of pyruvate dehydrogenase complex ...