Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder that causes red blood cells to break down. This can lead to symptoms and complications ranging from discoloration of urine to leukemia and ...
A acquired deficiency in the PIGA gene alters red blood cells. Paroxysmal nocturnal hemoglobinuria results when these altered cells replicate. Medications can stop the breakdown of red blood cells and ...