How do bacteria avoid wasteful production of unnecessary proteins when their genes are always on? The answer lies in regulating the operon. As trp levels increase, trp binds to trpR, causing a ...
As an undergraduate at Radcliffe College—Harvard's allgirl sister institution—in the 1960s, Susan Gottesman earned pocket money working as a technician in Jim Watson's Harvard lab. "I would hear ...
Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...
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