In a recent study published in the journal PLOS One, researchers present the crystal structure of an anti-non-structural protein 9 (nsp) specific nanobody in complex with the severe acute respiratory ...
A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in ...
Researchers identify JNK kinase as a key host factor driving coronavirus replication, revealing a potential antiviral target.
Virus entry is thought to involve binding a unique receptor for cell attachment and cytosolic entry. For SARS-CoV-2 underlying the COVID-19 pandemic, angiotensin- converting enzyme 2 (ACE2) is widely ...
Researchers have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection. The team uncovered differences in the innate immune and ...
Having caused over 6.2 million deaths globally ongoing, the COVID-19 pandemic since 2020 continues to pose a serious public health challenge. While the SARS-CoV-2 receptors angiotensin-converting ...
High-resolution images provide clarity into how viral proteins are separated by a protease, an important step during virus replication that is targeted by an approved COVID-19 drug. UNIVERSITY PARK, ...
Unraveling mechanisms underlying post-acute SARS-CoV-2 sequelae (long COVID) and finding therapeutic solutions require a full understanding of the causative role of SARS-CoV-2 persistence and/or ...
Scientists at UCSF QBI, University College London and the Icahn School of Medicine at Mount Sinai reported breakthrough findings in a study published Sept. 21, 2023, on convergent evolutionary ...