Although drug eruptions are often linked to the human leukocyte antigen (HLA), the mechanism of its involvement in presenting symptoms of the skin remains unclear. In a recent study, researchers used ...

That angry cluster of itchy red bumps might be more than just an annoying skin condition. While many skin irritations represent harmless reactions to environmental triggers, some persistent or unusual ...

A research group led by Professor Sungrim Seirin-Lee at Kyoto University Institute for the Advanced Study of Human Biology (WPI-ASHBi) leveraged hierarchical mathematical modeling to analyze the ...

Skin rashes are common among patients who complete hematopoietic cell transplantation (HCT). A new study found a high frequency of skin rashes among patients who underwent allogeneic hematopoietic ...

Skin rashes can have many different causes, one of which is medications. The symptoms of drug-induced skin reactions can range from a mild itchy rash to more serious reactions, such as widespread ...

What caused a 14-year-old girl to develop chronic, intractable light-sensitive skin eruptions on her face, upper body, and extremities? That's what Ruth Ann Vleugels, MD, MPH, of Harvard Medical ...

Gottron sign consists of red-purple hypertrophic papules, atrophic erythema, or red-purple macules on the extensor surface of the distal interphalangeal (DIP) and proximal interphalangeal (PIP) joints ...

Using genetically engineered mice expressing a specific variant of HLA, researchers uncover the instrumental role of this protein in the development of drug eruptions. They found that when HLA binds ...