This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Spatial transcriptomics and gene expression analysis represent a transformative approach in biomedical research, integrating the spatial context of tissues with high-resolution profiling of gene ...

Researchers developed two computational tools to decode how cells communicate in tissues. sCCIgen creates realistic virtual ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

At AGBT, customers will present data demonstrating unparalleled scale and sensitivity in research spanning pulmonary fibrosis, prostate cancer, and 3D reconstructions of mouse brains Company expands ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene expression and mechanical forces within cells and tissues, uncovering ...

In a paper published in the journal Nature Neuroscience, researchers have mapped how stress events during pregnancy can ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...