TSC is a relatively common inheritable genetic disorder that occurs in approximately 1 in 6000 of the population and is characterized by the development of hamartomas in a variety of organs 1. Common ...
Two papers in the August 1 issue of Genes & Development explore the genetic interactions between two well-known tumor suppressor proteins, PTEN and TSC2. Together, the studies shed new light on the ...
Loss-of-function mutations in the NF1 tumor suppressor gene underlie the familial cancer syndrome neurofibromatosis type I (NF1). The NF1-encoded protein, neurofibromin, functions as a Ras-GTPase ...
Statins improve outcomes of non-surgical curative treatments in hepatocellular carcinoma patients: cohort study from Taiwan cancer registry. This is an ASCO Meeting Abstract from the 2016 ASCO Annual ...