Harvard Medical School

Researchers Now Understand How a New Class of Antivirals Works

Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...
Fred Hutch

For the first time (in cryo-EM): A3G and Vif structure revealed

Lentiviruses, the group of viruses that include HIV, have infected primates for millennia. The coexistence of two parties with opposing interests – in this case, lentiviruses for replication and the ...
News Medical

Researchers use cryo-EM to map Powassan virus structure at high resolution

As summer kicks into full gear and people are spending more time outside, there's one thing on many people's minds - ticks. Tick season is starting earlier and lasting longer, and ticks are popping up ...
EurekAlert!

Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses

Toward the goal of efficient editing of farm animals for genetic improvements, this study explores an upgraded form of nuclease PE (uPEn). Based on the resolved structure of the NiV polymerase L-P ...
BioTechniques

Docs unlock the pox: key insights into the molecular structure of poxvirus cores

Researchers utilize electron microscopy coupled with AlphaFold software to glean key insights into the structure of the core of poxviruses. Despite the global effort to eradicate Smallpox, achieved in ...
Purdue University

Software startup Molecular Intelligence improves structuring molecules from cryo-EM image data

WEST LAFAYETTE, Ind. — Purdue University experts in the College of Science and Rosen Center for Advanced Computing have launched Molecular Intelligence, a software company whose solutions help ...