Background Concomitant metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in patients with chronic ...
An 82-year-old man with alcohol-related cirrhosis (Child-Pugh class B), complicated by portal hypertension and a history of partial gastrectomy with Billroth I reconstruction for duodenal ulcer ...
The persistent absence of disease-modifying therapy for recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) represents one of the more conspicuous therapeutic gaps in gastroenterology.
Background Gut bacteria have been implicated in a wide range of health conditions, yet their potential role in preventing and treating muscle-wasting disorders remains largely unexplored. Objective We ...
Background PD-1 blockade has emerged as a promising approach for functional cure of chronic hepatitis B (CHB). Objective This study aimed to evaluate the safety profile of anti-PD-1 antibody (αPD-1), ...
Background Our previous genome-wide association study (GWAS) identified that chromosome 1p36.22 locus contributes to the risk of hepatocellular carcinoma (HCC). Objective We aimed to identify the ...
Background Metabolic dysfunction associated steatotic liver disease (MASLD), the most common chronic liver disease globally, may originate early in life. While maternal obesity is linked to offspring ...
Background Enterically transmitted hepatitis viruses, such as hepatitis A virus (HAV) and hepatitis E virus (HEV), remain notable threats to public health. However, stable and reliable animal models ...
1 Department of Pathology, Brigham and Women’s Hospital, Boston, MA, USA, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA, and Harvard Medical School, Boston, MA, USA 2 ...
Background: Impaired gastric accommodation may lead to dyspeptic symptoms. A non-invasive method using single photon emission computed tomography (SPECT) has been developed to measure gastric volumes.
Objective To validate Lyon Consensus criteria for diagnosing gastro-oesophageal reflux disease (GORD) by reflux monitoring. Design Manual review of impedance-pH tracings from patients with proton pump ...
Correspondence to Dr Johann von Felden, Department of Internal Medicine, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany; j.von-felden{at}uke.de; Dr Augusto Villanueva, Liver Cancer Program, ...