Scientists have determined structures of a transporter protein involved in the movement of neurochemicals such as serotonin and dopamine, unearthing multiple mechanisms that can guide drug development ...

Scientists at St. Jude Children’s Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal ...

A new study is shedding light on our understanding of the molecular origins of some forms of autism and intellectual disability. Researchers were able to successfully capture atomic resolution images ...

Glutamate transporters pump glutamate from the synaptic cleft back into brain cells after its release during neurotransmission. A new study by Weill Cornell Medicine investigators has found that free ...

Your body functions using chemical messages that are directed throughout your system with specific targets. These chemical messages are carried by neurotransmitters, which act as a messenger directing ...

Glycine is a major inhibitory neurotransmitter that reduces nerve activity, helping to regulate pain signals, motor control and sensory processing. Glycine transporter 2 (GlyT2) is a key regulator of ...

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key ...

Why are some people more prone to anxiety than others? Researchers have shed light on the evolution of brain mechanisms underlying anxiety. The evolutionary origins of monoamine neurotransmitters like ...

Amphetamine is a psychostimulant that has been used to treat a variety of brain dysfunctions. However, it is a highly abused drug. In fact, amphetamine and amphetamine-derived compounds such as ...