Bacteria need to constantly adapt to compete against other species for nutrient sources and to survive against threats such as antibiotics and toxins. In an effort to understand how bacteria control ...

A bacterial protein helps to stop transcription -- the process of making RNA copies of DNA to carry out the functions of the cell -- by causing the cellular machinery that transcribes the DNA to pause ...

To better understand how RNA in bacteria gives rise to protein--and along the way, target these processes in the design of new antibiotics--researchers are turning their attention to the unique way ...

Transcription initiation involves the interaction of DNA-dependent RNA polymerase with promoters. In bacteria, this is a highly regulated process. Many regulators interact directly with the bacterial ...

Bacterial transcription is a production line of copying over genetic instructions from double stranded DNA to produce RNA, which is then used for the subsequent production of proteins that the ...

Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H 2 S) signaling, report researchers from Japan. Heme binding promotes the reaction of H 2 S with the transcription ...

The common commensal gut bacterium Bacteroides thetaiotaomicron uses phase separation of the transcription termination factor Rho to colonize and thrive in the mammalian gut, according to a new study ...

There are many processes that take place in cells that are essential for life. Two of these, transcription and translation, allow the genetic information stored in DNA to be deciphered into the ...

Preserving its DNA ought to be a cell’s top priority. But bacteria slow their DNA repair to a crawl in favor of proofreading gene transcripts. Evolution is a game of trade-offs. Every trait an ...

Transcriptional activator proteins in bacteria often operate by interaction with the C-terminal domain of the α-subunit of RNA polymerase (RNAP). Here we report the discovery of an "anti-α" factor Spx ...