rmdopen.bmj5d
Impaired coagulation parameters in early RA are restored by effective antirheumatic therapy: a prospective pilot study
Objectives To assess the effect of treatment on haemostatic parameters in patients with early rheumatoid arthritis (RA).
rmdopen.bmj3d
Table of contents
Original research: Body composition is associated with changes in health-related quality of life in patients with knee and/or hip osteoarthritis (2 January, 2025) ...
rmdopen.bmj1d
Protein and DNA methylation-based scores as surrogate markers for interferon system activation in patients with primary Sjögren’s syndrome
Objective Standard assessment of interferon (IFN) system activity in systemic rheumatic diseases depends on the availability of RNA samples. In this study, we describe and evaluate alternative methods ...
rmdopen.bmj8d
Transcutaneous auricular branch vagal nerve stimulation as a non-invasive add-on therapeutic approach for pain in systemic sclerosis
Objective Systemic sclerosis (SSc) is an autoimmune disease with health-related quality of life (HRQoL) high impairment. Pain is of paramount importance to be targeted by therapeutical approaches. Our ...
rmdopen.bmj1d
IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis
Objective Animal models for human diseases are especially valuable for clarifying molecular mechanisms before or around the onset. As a model for rheumatoid arthritis (RA), we utilise knock-in mice ...
rmdopen.bmj3d
The effect of rituximab on patient reported outcomes in the preclinical phase of rheumatoid arthritis: 2 year data from the PRAIRI study
Objectives Early treatment of individuals at risk of developing rheumatoid arthritis (RA-risk) in the preclinical phase has the potential to positively impact both patients and society by preventing ...
rmdopen.bmj2d
Body composition is associated with changes in health-related quality of life in patients with knee and/or hip osteoarthritis
Objective The objective of this study was to analyse the association between body composition and changes in health-related quality of life (HRQoL) of patients followed for hip and knee osteoarthritis ...
rmdopen.bmj4d
Physical workload is associated with increased risk of rheumatoid arthritis: results from a Swedish population-based case–control study
Objectives This study investigated: (1) the association of physical workload (PW) and risk of rheumatoid arthritis (RA); (2) the potential interactions between PW and the genes in the human leucocyte ...
rmdopen.bmj8d
Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis
Objective The first biomarker associated with the rheumatoid arthritis is rheumatoid factor (RF) and since the earliest reports a role has been proposed in the diagnosis and in the prediction of ...
rmdopen.bmj7d
Towards secondary prevention of early knee osteoarthritis
Osteoarthritis (OA) of the knee is the most common arthritic disease, yet a convincing drug treatment is not available. The current narrative review focuses on integration of scientific evidence and ...
rmdopen.bmj12d
Steps in implementing a health economic evaluation
Within the health technology assessment framework, 1 an economic evaluation compares health technologies in terms of their costs, clinical effectiveness, side effects, impact on health-related quality ...