A new database and mobile app called BRCA Exchange is making it easier for experts to share information about cancer-related gene mutations. Summary Clinical genetics experts from MSK and other ...
Germline BRCA mutations have an adverse impact on both progression-free and overall survival in patients with hormone receptor-positive/HER2-negative metastatic ...
BRCA genetic mutations, which are 10 times more common among Ashkenazi Jews than among the general U.S. population, significantly increase the risks of developing breast cancer and ovarian cancer. In ...
Deescalated nab-paclitaxel plus carboplatin showed higher efficacy than nab-paclitaxel plus gemcitabine in early-stage TNBC patients. BRCA1/2 mutation carriers exhibited a more pronounced pathologic ...
Lynparza significantly improves iDFS, DDFS, and OS in BRCA1/2 mutation-positive, HER2-negative high-risk breast cancer patients. The trial's six-year analysis shows consistent benefits across all ...
The authors acknowledged that longer follow-up (up to 20 years) may be required to detect a potential survival benefit, ...
Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast ...
Preliminary genomic analysis has linked defects in natural killer cell pathways to earlier breast cancer diagnosis in women ...
Results that may be inaccessible to you are currently showing.
Hide inaccessible results