Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

Researchers describe minimal versatile genetic perturbation technology (mvGPT). Capable of precisely editing genes, activating gene expression and repressing genes all at the same time, the technology ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

A newly identified enzyme appears to control tau production, brain inflammation, and aging. Researchers at the University of ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Uppsala University Hospital-led investigators report that gene-edited donor islet cells survived 12 weeks inside a man with long-standing type 1 diabetes without any immunosuppressive medication.

Hair loss and graying, the earliest visible hallmarks of skin aging, result from the functional decline of hair follicle stem cells (HFSCs) and their niche. Dr. Zhao and colleagues conducted a ...