Scientists spent decades uncovering the mechanisms that regulate the human body’s response to oxygen. The implications on the way we understand disease could be significant. This article was produced ...
SALT LAKE CITY— For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified ...
Cells adapt to hypoxia by a cellular response, where hypoxia-inducible factor 1a (HIF-1α) becomes stabilized and directly activates transcription of downstream genes. In addition to this "canonical" ...
Randomized controlled trials have generally shown a benefit from accelerated radiotherapy in head and neck squamous cell carcinoma (HNSCC). However, the large randomized United Kingdom trial CHART ...
The research conducted by Professor Zou Zui and his team focuses on the immunoregulatory mechanisms in sepsis. As a ...
CORVALLIS, Ore. - A tidepool crustacean's ability to survive oxygen deprivation though it lacks a key set of genes raises the possibility that animals might have more ways of dealing with hypoxic ...
“Lassie,” “Toto,” and Fellow Pet Dogs: Poised to Lead the Way for Advances in Cancer Prevention Type II papillary RCC can occur in both a sporadic (nonhereditary) and inherited form. Hereditary ...
A certain biological pathway drives the inflammation seen in the skin disease psoriasis. A certain biological pathway, a set of linked reactions in the body, drives the inflammation seen in the skin ...
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