The application of mass-spectrometry-based proteomics to profiling whole organs or tissues requires that the samples be fractionated to increase the detection limits of analysis 1,2,3,4. We have ...

Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding where ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

Using a high-throughput fluorescence microscopy system and machine learning algorithms, oxidative stress-related changes in protein localization have been mapped by researchers from Japan. Furthermore ...

Researchers have developed a new pH probe and imaging technique to provide researchers more information when studying diseases like cancer and Alzheimer's. In the field of scientific research, details ...

Researchers can now rapidly isolate and chemically characterize individual organelles within cells. The new technique tests the limits of analytical chemistry and rapidly reveals the chemical ...

Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis of ...