Angioedema, a type of swelling that affects the skin and tissues of the body, commonly affects the lips. Angioedema is a type of swelling that affects the deep tissues of the skin and other systems.

Orofacial granulomatosis is a rare skin condition that causes swelling in the face, mouth, or lips. The cause is often unknown, but experts think it’s related to allergies or an immune reaction.

Infections, injuries, jaw problems, and cancer can all cause mouth pain. The location and type of pain, plus any other symptoms that occur with it, can help with identifying the cause. The pain may ...