BMJ Evidence-Based Medicine

Methylphenidate denied access to WHO’s list of essential medicines for the third time

Attention-deficit/hyperactivity disorder (ADHD) affects 3%–5% of children and about 2.5% of adults, though prevalence varies ...
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Efficacy of smartphone apps used alone or with traditional interventions for smoking cessation: a systematic review and meta-analysis

Objectives To assess the efficacy of smartphone apps for smoking cessation (SC) used alone or combined with traditional interventions, and to determine whether apps based on psychological-behavioural ...
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A primer to planetary health in evidence-based medicine and clinical decision-making

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Using and distinguishing evidence from non-randomised studies of interventions

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Online First

Toward automating GRADE classification: a proof-of-concept evaluation of an artificial intelligence-based tool for semiautomated evidence quality rating in systematic reviews ...
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Overdiagnosis: what it is and what it isn’t

Correspondence to Professor John Brodersen, Centre of Research & Education in General Practice, Department of Public Health, University of Copenhagen, Faculty of Health Sciences, Copenhagen 1014, ...
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Wrong guidelines: why and how often they occur

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Framework for the synthesis of non-randomised studies and randomised controlled trials: a guidance on conducting a systematic review and meta-analysis for healthcare decision ...

Introduction: High-quality randomised controlled trials (RCTs) provide the most reliable evidence on the comparative efficacy of new medicines. However, non-randomised studies (NRS) are increasingly ...
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Reducing the environmental impact of healthcare to improve health, sustainability and equity

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28 Dealing with retrieval bias for an evidence-informed individual patient data network meta-analysis

Objectives The synthesis of individual patient data (IPD) from randomised clinical trials (RCTs) can strengthen evidence used for decision-making. Network meta-analyses (NMA) modelling IPD usually ...
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011 Development and nation-wide implementation of a patient decision aid including real-world outcome information to support shared decision making about treatment for non ...

3 Department of Clinical Pharmacy, St. Antonius Hospital, Utrecht/Nieuwegein, The Netherlands 4 Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical ...
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Registration of health and medical research

Registration of health and medical research is an effective way of improving the transparency and credibility of evidence. Registration involves pre-specifying the research objectives, design, methods ...