NFL Week 13 features a a number of key divisional matchups. In an important AFC South battle, the Houston Texans look to pull within one game of the division lead when they meet the Indianapolis Colts.

The Buffalo Bills and the Pittsburgh Steelers meet Sunday in Week 13 at Acrisure Stadium in Pittsburgh, Pennsylvania.

NFL Week 13 picks, predictions, win probabilities for Packers-Lions, Rams-Panthers, Texans-Colts, Vikings-Seahawks, Raiders-Chargers, games this week.

With that, we are on to the picks for this week. As always, we remind you that picks for over/unders and spread picks might vary a bit based on when each individual selector punched their picks into the system that our friends at Tallysight have provided. For the latest lines and numbers, be sure to check in with your sportsbook of choice.

RotoBaller's Week 13 NFL DFS value plays, sleeper picks, and tournament stacks for daily fantasy football on FanDuel, DraftKings, and Yahoo. Win big in DFS with our expert research and advice.

KC Joyner's confidence picks have been on a roll lately. This week, his top picks are the Seahawks, Rams and Broncos.

The Tennessee Titans take on the Jacksonville Jaguars on Sunday, and here are three reasons for optimism in Week 13.

Jamie's DraftKings NFL DFS Week 13 picks, value plays, DFS sleepers for the main slate (2025). His top DK plays and value picks for daily fantasy football lineups.