Systemic lupus erythematosus (SLE) is a classic immune complex-mediated autoimmune disease that arises from the loss of tolerance to specific self-antigens (such as nuclear antigens). It can cause ...

Potential to bring nuclear power, scalable eSAF production, and environmental-attribute monetization together into a single, integrated clean-energy platform. Exploring advancing next-generation eSAF ...

Cancer drug resistance is the devastating reason that treatments fail and cancers metastasize, spreading to distant sites seeding new resistant tumors elsewhere in the body. Combating the problem has ...

Hereditary hemorrhagic telangiectasia (HHT) can cause recurrent, severe epistaxis, as well as anemia and reduced quality of life. The disease remains without licensed therapies worldwide. In this ...

Introduction: One goal of Precision Cardio-Oncology is to identify and ultimately clinically exploit a fundamental understanding of shared signaling pathways in cardiovascular disease and oncologic ...

Prostate cancer (PC), including castration-resistant disease (CRPC), remains largely driven by dysregulated androgen receptor (AR) signaling. While androgen deprivation therapy (ADT) combined with ...

Schematic representation of different strategies targeting TGF-β signaling for liver fibrosis therapy. TGF-β signaling inhibitors hold important therapeutic potential for hepatic fibrosis. Although ...