The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

A 3D liver model was engineered by a team of researchers, that accurately replicates the connection between liver cells (hepatocytes) and scarring cells (stellate cells) in the condition of fibrosis.

A new liver-on-a-chip made from natural collagen could offer a more realistic model for drug screening, as well as for the study of pathological diseases such as liver cancer and cirrhosis. The new ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and ...

The liver is the body's control tower for metabolism, powering vital functions like converting nutrients to glucose, storing fat and breaking down toxins. Over a third of the world, however, is ...

Periportal assembloid, with the three component cell types visualized: cholangiocytes in pink, portal fibroblasts in green, and hepatocyte nuclei in blue; all cell borders are visualized in white. New ...