MicroRNAs, whose discovery was recognized with the 2025 Nobel Prize in Physiology or Medicine, are central regulators of gene ...

Aβ is believed to play a significant role in synaptic degeneration observed in Alzheimer’s disease (AD) and is primarily investigated as a secreted peptide. However, the contribution of intracellular ...

Researchers have revealed insight into why embryos erase a key epigenetic mark during early development, suggesting this may have evolved to help form a placenta. Researchers at the Francis Crick ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

Some of our species’ earliest ancestors may have spent a lot more time eating salad than steak. Diet has been a crucial component of human evolution, says Tina Lüdecke, a geochemist at the Max Planck ...

The study presents important findings that reveal SEPHS2 and VPS37C as new potential drug targets for dasatinib and hydroxychloroquine respectively in addition to confirming known targets of these ...

Introduction: The ongoing emergence of SARS-CoV-2 variants poses significant challenges to existing therapeutics. The spike (S) glycoprotein is central to both viral entry and cell-to-cell ...