Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize ...
Agonists for pregnane X receptor can prevent cholesterol gallstone disease in mice, according to a study published in Gastroenterology. Researchers compared levels of bile salts and cholesterol in PXR ...
The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16α-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression and protect the body from ...
Pregnane X receptor (PXR) is a transcription factor that plays a crucial role in maintaining bile acid homeostasis by regulating major metabolizing enzymes and transporters.
Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize ...
Several chemicals that can accumulate to high levels in our body (for example, BPA and some pesticides) have been recently linked to an increased risk of cancer and/or impaired responsiveness to ...
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