One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.
The blood-brain and blood-retinal barriers are protective systems that prevent harmful substances from entering the brain and ...
Abstract: Protein-protein interactions (PPIs) play a crucial role in cellular biochemical reactions. Computationally mining PPI can help us better understand cellular regulatory mechanisms. Most ...
The application of deep learning algorithms in protein structure prediction has greatly influenced drug discovery and development. Accurate protein structures are crucial for understanding biological ...
If you're one of the 13% of American adults who has taken a GLP-1 drug for weight loss, you may know that while fat seemingly melts away, so too does muscle. And if you're not one for weights, or have ...
In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.
# Replace $MULTICOM4_INSTALL_DIR with your MULTICOM4 installation directory bash $MULTICOM4_INSTALL_DIR/tools/alphafold-v2.3.2/scripts/download_all_data.sh <YOUR ...
Generating all-atom protein structures is a significant challenge in de novo protein design. Current generative models have improved significantly for backbone generation but remain difficult to solve ...
In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of deep learning techniques in revolutionizing protein structure prediction. The ...
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