Cell-surface proteins are critical therapeutic targets and are vital to cellular communication, signaling, and homeostasis.

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

Geneticist Dr. Robert Green is sequencing the DNA of healthy newborns to find hidden disease risks. This knowledge can save ...