Coach Kyle Shanahan said tests Monday confirmed the initial diagnosis that Aiyuk tore his ACL and would need major ...

Parsons was out for a 20-17 victory at Pittsburgh and a 47-9 loss to Detroit, the latter a third consecutive home defeat in ...

One anonymous NFL executive thinks the San Francisco 49ers should look into trading Brock Purdy to go with a "cheaper" ...

Podcaster Bill Simmons said the San Francisco 49ers are runaway favorites for his self-anointed "year from hell" team for the ...

San Francisco 49ers rookie Ricky Pearsall made his NFL debut on Sunday, Oct. 20, two months after he was shot in the chest ...

The visitor’s sideline at Levi’s Stadium is in full sun, but the Chiefs hatched an unusual plan to keep players cool.

The 49ers fell to 3-4 as their offense loses more players and their defense fails again to thwart the Chiefs and ...

The Chiefs are the NFL's only unbeaten team at 6-0 and yet, "We’re gonna be so much better. There’s so much more we can do.” ...

This is surprising. Deebo Samuel apparently is a trade deadline name to watch according to The Athletic's Dianna Russini.

Aiyuk went to the locker room on a cart due to an undisclosed injury at halftime of Sunday's game against the Chiefs, Eric Branch of the San Francisco Chronicle reports.

According to Eric Branch of the San Francisco Chronicle, the San Francisco 49ers are signing former Green Bay Packers kicker ...

A potential Aidan Hutchinson replacement is lined up for the Lions, the Chiefs and Panthers could strike a deal, and Deebo ...