Aperture Therapeutics is advancing APRTX-003, an RNA-based antisense therapy targeting MMP9, as a potential ALS treatment.

Scientists have discovered a new CRISPR mechanism with precise activity, expanding the potential applications of the existing ...

Researchers from Würzburg, Braunschweig, and the US identifiy Cas12a3 nuclease showing precise activity. Their study is ...

One of the most well-studied cellular responses is how they react during times of stress, such as when the temperature gets ...

Background Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality with limited therapeutic options. Despite ...

We can replace joints, lenses, even organs—but not the brain. As neuroscience unravels the mechanisms of neurodegeneration, ...

The extreme weight loss seen in many late-stage cancer patients, known as cachexia, is far more than a cosmetic side effect.

Scientists extracted RNA from a 130-year-old specimen, uncovering which genes were active before the animal went extinct.

It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...

Cancer patients often lose excessive amounts of weight. This affects up to 80% of patients and is mainly due to a decrease in muscle mass and fatty tissue. This cancer-induced cachexia (CIC) is ...

Abstract: Messenger RNA (mRNA) exerts its specific functions at distinct subcellular locations, making the localization of mRNA within cells critically important for studying gene expression and cell ...

Researchers have visualized how a large RNA molecule assembles itself into a functional machine. RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like ...