Eight months after the Kansas City Chiefs edged the San Francisco 49ers for a Super Bowl title, the reigning champions ...

Already missing one of their top three receivers, the 49ers ruled out Brandon Aiyuk (knee) and Deebo Samuel (illness) for the ...

49ers receiver Brandon Aiyuk was carted off from the sideline before halftime Sunday. Aiyuk was injured with 37 seconds left ...

San Francisco 49ers star wideout Deebo Samuel left his team's home game against the Kansas City Chiefs on Sunday with an illness and was later ruled out.

The 49ers’ already depleted offense took a hit on Sunday as Brandon Aiyuk and Deebo Samuel were deemed out for the second ...

Las Vegas Raiders quarterback Aidan O'Connell departed Sunday's road game against the Los Angeles Rams in the first quarter ...

The San Francisco 49ers lost standout receivers Brandon Aiyuk and Deebo Samuel during Sunday's 28-18 loss to the visiting ...

San Francisco 49ers wide receiver Brandon Aiyuk was carted to the locker room during Sunday's game against the Kansas City ...

San Francisco 49ers star wide receiver Deebo Samuel has been ruled out for the remainder of Week 7 against the Kansas City ...

Deebo Samuel was felled by illness during warmups on Sunday afternoon. He's still expected to play against the Chiefs.

San Francisco 49ers wide receiver Brandon Aiyuk left Sunday's game with a knee injury and has been ruled out for the remainder of the contest. Aiyuk ...

The San Francisco 49ers are hosting the Kansas City Chiefs at Levi's Stadium in Santa Clara, California. While the 49ers ...