The Denver Broncos and the San Francisco 49ers will kick off their 2025 preseason at Levi's Stadium on Saturday.

The last NFL preseason game to kick off tonight is the San Francisco 49ers vs. the Denver Broncos in this rivalry matchup.

The Denver Broncos kicked off their preseason slate with a 30-9 victory over the San Francisco 49ers on Saturday. Check out ...

The 49ers just lost their preseason opener to the Denver Broncos by a score of 30-9. Here are the 49ers' grades for this performance.

Jarrett Stidham threw two touchdown passes, leading the Denver Broncos to a 30-9 victory over the San Francisco 49ers.

Eight quarterbacks who played at Alabama high schools and colleges threw passes in Saturday’s NFL preseason games.

Mac Jones is excited for the challenge to grow with San Francisco's offense after making his debut with the team Saturday.

Defensively, the Broncos poured it on, taking the ball away four times, and sacking the quarterbacks twice. Depth standouts ...

The first preseason game is in the books for the San Francisco 49ers. They suffer a defeat at home to the Denver Broncos 30-9. As expected, all of the 49ers' s ...

The San Francisco 49ers didn't have the deepest linebacker room in the team's first preseason game, and it got thinner with ...

SportsLine simulated the new NFL season 10,000 times and revealed its 2025 Fantasy football QB, RB, WR, TE, kicker and ...

Optimism is running high among die-hard San Francisco 49ers fans as the new NFL season begins, despite the team missing the ...