When we asked Boston.com readers to weigh in on the verdict, more than 1,500 responded. The vast majority — 1,310 readers, or 85% — said they were not surprised by the outcome. Another 171 readers (11%) reported being surprised by the verdict, while 52 (3%) said they were unsure.

"I was happy for Karen Read and her family of course. I think justice was served," Prado said. "But seeing John O'Keefe's family leaving the courthouse, was melt my heart. I'm a mother and I saw her pain through all those days."

Karen Read’s second murder trial was a rematch for the lawyers after the first ended in a hung jury last year. CNN correspondent Jean Casarez answers key questions about the case after Read was acquitted of murder Wednesday.