Analyst Dane Brugler of The Athletic released his latest mock draft, projecting the San Francisco 49ers to strengthen both ...

Exploring San Francisco 49ers quarterback Brock Purdy's future with the team: Comparing his salary vs potentially signing Sam Darnold at the position.

Health officials have identified another possible case of bird flu in a child — this time in San Francisco. The San Francisco ...

NFL coaches are now the youngest in 'Big Four' leagues. Does that correlate to performance? USA TODAY Sports' Coaches Project ...

Lurie has proposed what he's dubbed a "fentanyl state of emergency ordinance" to the Board of Supervisors. The ordinance ...

Plus: A stomach flu vaccine, the health impacts of California’s wildfires, lots of nine-figure deals for healthcare startups ...

The San Francisco 49ers are searching for new defensive and special teams coordinators, and an offseason of change for their ...

While Roki Sasaki has gotten tons of headlines as an international free agent, the San Francisco Giants signed someone who ...

Daniel Lurie, an heir to the Levi Strauss fortune was sworn as the San Francisco's 46th mayor. We discuss his plans for the ...

People in San Francisco's Fillmore district are pressuring city leaders to take action before the closure of the only full ...

The NFC West will be difficult again in 2025. The division-winning Los Angeles Rams just upset the Minnesota Vikings in the ...

The 49ers A.P.E.X. Employee Resource Group came together to create an apparel line that pays homage to the roots of AAPI ...