Abstract. In recent years, accumulation of mitochondrial reactive oxygen species (ROS) has been shown to limit the proliferative capacity and intratumoral persistence of CD8+ T cells, but the ...

1Surveillance, Prevention, and Health Services Research, American Cancer Society, Atlanta, Georgia. *Corresponding Author: Elizabeth J. Schafer, Surveillance ...

Department of Physiology, University of Kentucky Schoof of Medicine, Lexington, Kentucky. *Corresponding Author: Erhard Bieberich, Department of Physiology, University of Kentucky College of Medicine, ...

1The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. 2The Lung Cancer Precision Medicine Center of Excellence, Johns Hopkins University ...

1Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. 2Broad Institute of Harvard and MIT, Cambridge, ...

*Corresponding Author: Anne McTiernan, Public Health Sciences Division, Fred Hutchinson Cancer Center, 1100 Fairview Avenue North, P.O. Box 19024, Seattle, WA 98109. E-mail: [email protected] ...

Creighton University School of Medicine, Omaha, NE.

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Abstract. We investigated the effect of small molecules extracted from the latex of Calotropis procera (CPPE) to act as inhibitors of Heat Shock Protein 90 (HSP90), a key molecular chaperone co-opted ...

University of Arkansas for Medical Sciences, Little Rock, AR.

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1Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany. 2Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer ...