The growth rate of the atmospheric abundance of methane (CH 4) reached a record high of 15.4 ppb yr −1 between 2020 and 2022, but the mechanisms driving the accelerated CH 4 growth have so far been ...

We demonstrate that substitutionally inert octahedral metal complexes, such as the iridium (III) carbene complex (1a), provide a useful source of potent inhibitors for unexplored oncogenic protein ...

Cell-based therapy using satellite stem cells (SSCs) holds tremendous potential for enhancing muscle regeneration. However, conventional isolation methods often yield heterogeneous cell populations ...

Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

The identification of SLC35F2 as the eukaryotic transporter of queuine and queuosine is key to understanding how these micronutrients are salvaged from the human gut and distributed to different body ...

Evolutionary game theory (EGT) has been pivotal in the study of cooperation, offering formal models that account for how cooperation may arise in groups of selfish, but simple agents. This is done by ...

Circulating monocytes are recruited to the tumor microenvironment, where they can differentiate into macrophages that mediate tumor progression. To reach the tumor microenvironment, monocytes must ...

Policies that alter land use affect food production, wild species, and greenhouse gas emissions simultaneously. However, policy analyses rarely if ever consider these connections and instead typically ...

Heritable microbes can regulate insect reproduction in diverse ways (1). For example, some symbionts which have been called reproductive manipulators, cause cytoplasmic incompatibility, male-killing, ...

Using novel mouse models, we establish cyclin-dependent kinase 12 (CDK12) as a bona fide tumor suppressor gene in tubo-ovarian high-grade serous carcinoma, demonstrating that its loss drives increased ...

Crystallization of the lunar magma ocean yielded a chemically unique liquid residuum named KREEP. This component is expressed as a large patch on the near side of the Moon and a possible smaller patch ...

As former EPA and ORD scientists, we argue that dismantling ORD would not only jeopardize human and environmental health, but also weaken American science and global competitiveness. ORD’s vital—yet ...