What Did Kaley Cuoco Say When Asked About Playing Penny Again? The Role Play actress played the role of the free-spirited Penny throughout all 12 seasons of The Big Bang Theory. I

"It was some of the best years of my life, and some of the most fun I've ever had," Cuoco said of her time on the hit sitcom.

As The Big Bang Theory universe expands, Kaley Cuoco would enthusiastically join its orbit. Speaking to People ahead of the second season debut of her Peacock comedy-thriller Based on a True Story, Cuoco reflected on her starring role as Penny with nostalgic fondness.