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  1. Naloxone - Wikipedia

    Naloxone, sold under the brand name Narcan among others, is an opioid antagonist, a medication used to reverse or reduce the effects of opioids. [14] For example, it is used to restore …

  2. NARCAN® Nasal Spray

    Naloxone, the active ingredient in NARCAN® Nasal Spray, competes with opioids to bind with the same receptors in the brain, reversing the effects of an opioid overdose in 2 to 3 minutes.

  3. Narcan: Dosage, How It's Given, How It Works, Uses, and More

    Sep 28, 2023 · Narcan is used for emergency treatment of opioid overdose. It’s an opioid antagonist, which means it works by blocking certain receptors (attachment sites) in your body …

  4. Narcan Nasal Spray: Opioid Overdose, Instructions and more

    Jul 11, 2024 · Narcan nasal spray (naloxone) is an over-the-counter medicine used to treat an opioid overdose emergency, Narcan works by rapidly reversing the opioid's effects.

  5. 5 Things to Know About Naloxone | Overdose Prevention | CDC

    May 2, 2024 · Naloxone, for example Narcan®, is a medicine that can help people who are overdosing on an opioid. Opioids include prescription medications, heroin, and fentanyl.

  6. How Narcan works: Mechanism of action explained - Medical …

    Jul 3, 2025 · Narcan (naloxone) is an over-the-counter (OTC) medication that treats opioid overdose. Its mechanism of action is to quickly block opioids in your system.

  7. FDA Approves New Drug That Reverses Effects Of Narcan

    4 days ago · “Narcan use in this country is a major public health concern for Americans, who are often left watching helplessly as friends and loved ones succumb to the resuscitating effects of …

  8. What is Narcan (naloxone)? Uses, how it works, and where to get it

    May 30, 2025 · Learn what Narcan (naloxone) is, how it reverses opioid overdoses, where to get it, and how to use it safely with support from QuickMD

  9. Frequently Asked Questions for NARCAN® Nasal Spray

    NARCAN® Nasal Spray was designed to rapidly reverse the effects of a life-threatening opioid emergency. It is used to revive someone during an overdose from many prescription pain …

  10. How does Narcan work? Mapping how it reverses opioid …

    Nov 26, 2025 · Naloxone can reverse an overdose in minutes, but exactly how it does this at the molecular level has previously been unclear.