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  1. The Sponge Hypothesis of Sarcopenia: Functional Hyponatremia …

    2 days ago · Background and Aims: Dilutional hyponatremia and sarcopenia (SP) are prognostic factors associated with portal hypertension (PHT) in chronic liver disease (CLD). Because …

  2. May 21, 2022 · A hypothesis is an educated guess or statement about the relationship between 2 or more variables 2,3. Scientific hypothesis generation is a critical step in scientific research …

  3. Estimating Blood Pressure from the Electrocardiogram: Findings of …

    Jul 25, 2025 · Approach In this study, machine-learning (ML) models were developed to explore this hypothesis by estimating BP from 30-second ECGs using an extensive dataset from …

  4. Hypothesis-generating analysis of mutational signatures in …

    Oct 9, 2025 · Clock-like signatures show associations with parental and patient age as well as SES, potentially indicating some age-dependent differences. These results should inform …

  5. Hypothesis-driven patterns of intracranial exploration in

    Jul 22, 2024 · Using semiological observations and a detailed cytoarchitectonic analysis, we propose a novel hypothesis classification system of four hypotheses in TLE and describe this …

  6. Altered sensorimotor-association axis patterning of global …

    Nov 2, 2025 · To test this hypothesis, we first demonstrate that unsupervised data-driven techniques can detect 2 autism subtypes (high versus low) with very high accuracy (92%) in …

  7. Defining the Clinical Complexity of hEDS and HSD: A Global …

    Jun 6, 2025 · Instead, our findings support the hypothesis that hEDS and/or HSD may represent complex syndromes in which connective tissue fragility may be a downstream consequence …

  8. 4 days ago · hyponatremia. 3. This study represents a cross-sectional, hypothesis-generating pathophysiological model; therefore, no causal relationship can be inferred between serum …

  9. Embryonic Germ Layer Origin as a Potential Determinant of Cancer ...

    Jun 17, 2025 · This systematic review examines the hypothesis that therapeutic efficacy correlates with the developmental origin of neoplasms, specifically proposing differential …

  10. Dec 1, 2025 · Green checkmarks indicate proxies where the direction of difference supports the hypothesis that celiac disease is associated with less gynoid fat. Only gynoid region percent …