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  1. JAK2 Gene Mutation: Causes and Related Conditions

    Sep 5, 2025 · The Janus kinase 2 (JAK2) gene directs cells to make the JAK2 protein, which stimulates cell growth and division. Learn what can cause a JAK2 gene mutation and …

  2. Janus kinase 2 - Wikipedia

    Janus kinase 2 (commonly called JAK2) is a non-receptor tyrosine kinase.

  3. What Is the JAK2 Mutation and What Does It Mean?

    Aug 2, 2025 · Janus Kinase 2 is involved in cell signaling pathways, acting like a switch that turns on or off various cellular activities. Its primary role involves responding to signals from growth …

  4. JAK2 Mutation Can Lead to Essential Thrombocythemia Diagnosis

    Oct 4, 2024 · About 50 to 60 percent of people with essential thrombocythemia have the genetic mutation JAK2. Learn what they are, and what to talk to your doctor about.

  5. What conditions does the JAK2 gene relate to? - Medical News …

    Jun 9, 2023 · The JAK2 gene is a protein-coding gene of the Janus kinase family. It initiates several cellular signaling processes, including cell division, immunity, and tumor formation.

  6. Roles of JAK2 in Aging, Inflammation, Hematopoiesis and …

    In this review we aim to summarize the current knowledge on JAK2 in clonal hematopoiesis during aging, the role of JAK-signaling in inflammation and lymphocyte biology and JAK2 …

  7. JAK2 gene: MedlinePlus Genetics

    The JAK2 gene provides instructions for making a protein that promotes the growth and division (proliferation) of cells. This protein is part of a signaling pathway called the JAK/STAT …

  8. JAK2 Gene Fusion Found Across Cutaneous T-Cell Lymphomas

    22 hours ago · JAK2 gene fusion appears across multiple CTCL types, shaping diagnosis and treatment opportunities. Learn more about its growing clinical relevance in lymphoma research.

  9. JAK2 Gene - GeneCards | JAK2 Protein | JAK2 Antibody

    Nov 13, 2025 · JAK2 (Janus Kinase 2) is a Protein Coding gene. Diseases associated with JAK2 include Polycythemia Vera and Thrombocythemia 3. Among its related pathways are Signaling …

  10. JAK2 Blood Test Results Interpreted - HRF

    The JAK2 blood test is typically ordered when there is evidence of increased platelet counts of high levels of hemoglobin. This is an acquired mutation, not an inherited one, and creates a …