Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall role of a protein.

Oct 15, 2025 · Classification of protein families InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Family- and domain-based classifications are not always straightforward and can overlap, since proteins are sometimes assigned to families by virtue of the domain (s) they contain.

Click on ‘Protein summary’ in the left-hand menu to see a graphical display of the protein domains (Figure 18). The exon structure is shown as alternating shade of purple at the top, while the variants …

Sequence features differ from domains in that they are usually quite small (often only a few amino acids long), whereas domains represent entire structural or functional units of the protein (Figure 8).

A protein family is a group of proteins that share a common evolutionary origin, reflected by their related functions and similarities in sequence or structure.

The structure of each representative SCOP domain is displayed within the context of a given PDB entry and coloured according to the colouring schema shown at the upper left corner of the structure …

Domains are distinct functional and/or structural units in a protein that can exist in a variety of biological contexts. Sequence features include active sites, binding sites, post-translational modification sites …

A sequence alignment is a way of arranging the primary sequences of a protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between …

We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.