Mammalian target of rapamycin (mTOR) is a kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. [5][6] It also promotes the …

Oct 2, 2023 · The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular metabolism, catabolism, immune responses, autophagy, survival, proliferation, and migration, to …

TOR is found in 2 structurally and functionally distinct multiprotein complexes, TORC1 and TORC2. The 2 TOR complexes, like TOR itself, are highly conserved. Mammalian TORC1 (mTORC1) is …

Aug 19, 2025 · The mammalian target of rapamycin (mTOR) is a master regulator of cell growth, nutrient sensing, and metabolism. It acts like a central switchboard, integrating signals from food, hormones, …

Jul 8, 2025 · The mammalian/mechanistic target of rapamycin (mTOR) is an evolutionarily conserved multi-node signaling pathway that integrates critical environmental cues to control cellular growth.

Jul 8, 2025 · Decades worth of studies have intricately dissected the mTOR pathway to identify regulatory signals that are essential for regulating immune cell activation, differentiation, and …

2 days ago · New research focused on mTOR, the protein at the center of the most commonly altered pathway in cancer, which is the working engine of two different protein complexes, mTORC1 (shown …

A protein that helps control several cell functions, including cell division and survival, and binds to rapamycin and other drugs. mTOR may be more active in some types of cancer cells than it is in …

The MTOR gene provides instructions for making a protein called mTOR. Learn about this gene and related health conditions.

Notably, mTOR plays a pivotal role in cardiovascular health and disease, particularly in the onset and progression of cardiac conditions. In this review, we discuss mTOR’s structure and function as well …