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Open Heart. is an open access journal by BMJ and BCS, publishing original research in cardiovascular medicine. Impact Factor: 2.8 Citescore: 4.6 All metrics >>
Four pillars of heart failure: contemporary ... - Open Heart
Mar 2, 2021 · The past two decades have heralded dramatic improvements in outcomes for people living with heart failure with reduced ejection fraction (HFrEF). 1 The more widespread implementation of disease modifying pharmacological therapies,2 supported by landmark trials of renin-angiotensin system inhibitors3 and beta-blockers4 have improved longevity despite a background of an ageing and increasingly ...
Homepage | Open Heart
An open access cardiology journal publishing original research and opinion on cardiovascular medicine at all study phases.
Timing of oral anticoagulation in atrial fibrillation patients after ...
Sep 18, 2024 · Results Among 708 registry patients with known AF before stroke and hospitalisation within 72 hours after stroke, 432 were anticoagulated at stroke onset. OAC was started according to the ‘1–3–6–12 days rule’ in 255 (39.2%) patients. Non-adherence to the ‘1–3–6–12 days rule’ was not associated with the composite endpoint within 3 months in 661 patients who (re-)started on ...
Epidemiology of myocarditis following COVID-19 or influenza and …
Nov 8, 2024 · Introduction. Myocarditis is an inflammatory process of the myocardium, and the most common cause is a viral infection such as influenza or coronaviruses.1 While most cases of viral myocarditis are mild with good prognosis, life-threatening cardiac dysfunction and arrhythmias may occur.2 3 Myocarditis can result in heart failure and sudden cardiac death and has been recognised as a rare ...
Optimal timing of oral anticoagulation initiation in patients with ...
Nov 26, 2024 · The optimal timing for initiating direct oral anticoagulants (DOACs) for secondary stroke prevention in patients with atrial fibrillation and acute ischaemic stroke remains controversial due to concerns about haemorrhagic transformation. This study aimed to analyse the efficacy and safety of early versus late DOAC initiation. Following the Preferred Reporting Items for Systematic Reviews and ...
Magnesium for the prevention and treatment of cardiovascular …
Jun 30, 2018 · Magnesium is an essential mineral found in the body. It is naturally present in many foods and is also available as a dietary supplement. 1 It serves as a cofactor in more than 300 enzymatic reactions, such as those responsible for regulating blood pressure, glycaemic control and lipid peroxidation. It is therefore also critical to the cardiovascular system.1 The adult body contains ...
Myo-inositol for insulin resistance, metabolic syndrome, polycystic ...
Mar 2, 2022 · Myo-inositol, also known as inositol (cyclohexanehexol), is a cyclic carbohydrate with six hydroxyl groups.1 For a long time, it was considered a B vitamin (vitamin B8). However, it is not considered an essential nutrient because it is formed from glucose. Each kidney makes around 2 g of myo-inositol per day, and the average dietary intake is 0.5–1.0 g/day.2 3 The liver and brain also ...
Detection of cardiac amyloidosis using machine learning on …
Dec 17, 2024 · Background Cardiac amyloidosis (CA) is an underdiagnosed, progressive and lethal disease. Machine learning applied to common measurements derived from routine echocardiogram studies can inform suspicion of CA.Objectives Our objectives were to test a random forest (RF) model in detecting CA.Methods We used 3603 echocardiogram studies from 636 patients at Cedars-Sinai Medical Center to train an ...
Effect of optimisation to contemporary HFrEF medical therapy with ...
Dec 2, 2024 · Introduction Heart failure with reduced ejection fraction (HFrEF) guidelines recommend ‘four pillars’ of medical therapy and device therapy if left ventricular ejection fraction (LVEF) remains ≤35% after 3 months optimum medical therapy.We conducted the first study to examine the effects of optimisation to contemporary medical therapy on cardiac reverse remodelling, as demonstrated by ...