Angela’s friends couldn't understand what had happened to the healthy, active, 43-year-old… Her story tonight at 10/9c on an all-new Dateline. | Dateline NBC

A medical mystery was about to turn into a full-on police investigation… Tonight on an all-new Dateline at 10/9c on NBC. | Dateline NBC

You’re witnessing something highly unusual… Watch the full story tonight at 9/8c on a classic 2-hour Dateline. | Dateline NBC

Cheryl had a nagging feeling… Where was her daughter, Kelsey? The full story tonight at 9/8c on a classic Dateline. | Dateline NBC

Hello, from Shauna, today’s Unofficial Dateline Friday Ambassador, with a reminder we’re on at 10/9c tonight. You may have missed that part ‘cause all you heard was the ALL NEW part…. We’re baaaaaack! | Dateline NBC

Dateline is heading to Nashville for its first live event ahead of its 3,000th episode. They announced the lineup of celebrity moderators, including actors Michael McKean, Annette O'Toole and Holly Robinson Peete! | Today Show